
ARTICLE LINKS: INTRATHECAL BACLOFEN THERAPY AND THE TREATMENT OF SPASTICITY.ORIGINAL ARTICLES Neurosurgery Quarterly.2007.Anderson, William S.PhD; Jallo, George I._ ABSTRACT: This monograph discusses the current treatment of spasticity via intrathecal baclofen (ITB) therapy.Describes the pathophysiology and the primary anatomic substrate of spasticity, and the current modern surgical and pharmacologic treatment options.Pumps are discussed in detail, including their implantation procedure, and basic modes of operation and design.ITB treatment are examined including infection, pump failure, and baclofen overdosing and withdrawal issues.From a recent cost-analysis study of ITB therapy are included, and promising future trends in the treatment of spasticity.Lippincott Williams & Wilkins, Inc. Copyright (c) 2007, Lippincott Williams & Wilkins.Rights reserved.By Lippincott Williams & Wilkins.
Read more
Netrin-1 receptor-deficient mice show enhanced mesocortical dopamine transmission and blunted behavioural responses to amphetamineGet more
Late-breaking clinical results from the inspire study revealed at the ers annual congress in stockholm