And other salicylates are known to reduce blood glucose in diabetic patients.Research accepted for publication in the Journal of Clinical Endocrinology & Metabolism reveals a similar beneficial effect among obese individuals by increasing the amount of insulin secreted into the bloodstream."The administration of a salicylate led to the lowering of serum glucose concentrations," said Jose-Manuel Fernandez-Real of the Institut d'Investigacio Biomedica de Girona and CIBEROBN Fisiopatologia de la Obesidad, Spain, and lead author of the study.Highlight the importance of further research on the possible therapeutic benefit of aspirin in the fight against type 2 diabetes.For their study, Fernandez-Real and his colleagues evaluated the effects of triflusal (a derivative of salicylate) on 28 subjects (nine men and 29 women).Average age of the participants was 48 years old and their average Body Mass Index (BMI) was 33.A BMI of over 30 is considered obese.Three, four-week treatment periods, the study participants received a 600 mg dose, a 900 mg dose, or a placebo once per day.The researchers found that administration of triflusal led to decreased fasting serum glucose.To their expectations, insulin sensitivity did not significantly change during the trial.However, significantly increased in relation to the dose size.In conjunction with the human studies, the researchers also conducted laboratory studies on insulin-producing cells (known as islets of Langerhans) from mice and humans.Researchers observed that triflusal significantly increased the insulin secreted by these cells."Aspirin therapy has been recognized to improve glucose tolerance and to reduce insulin requirements in diabetic subjects," said Fernandez-Real.Our knowledge, this is the first study to show that salicylates lowered serum glucose in non-diabetic obese subjects.That this effect was due to a previously unsuspected increase in insulin secretion rather than enhanced insulin sensitivity.Would you like to for our weekly ?The end of each week we'll send you an email containing links to the most popular articles (by page impression) from your chosen categories that appeared on News-Medical.That week.Will NOT be bombarded with advertising and you CAN unsubscribe at any time.More information or click here to view our .News-Medical.The worthy medical information: .Health News Disease/Infection News Devices/Technology News Healthcare News Medical Conditions Medical Procedures Medical Patent News Medical Research News Men's Health News Medical Science News Miscellaneous News Pharmaceutical News Medical Studies/Trials Women's Health News < Jump to News-Medical.This service in accordance with these .Please note that found on this website is designed to support, not to replace the relationship between patient and physician/doctor and the medical advice they may provide.Read more Lawyer crusading for avastin coverage dies of cancer
Get more Randomized trial of a single repeat dose of prenatal betamethasone treatment in imminent preterm birth
