пятница, 11 апреля 2008 г.

First-time use of bevacizumab for aggressive, metastatic hepatocellular carcinoma in an hiv/hepatitis b virus coinfected patient: a case report.

ARTICLE LINKS: FIRST-TIME USE OF BEVACIZUMAB FOR AGGRESSIVE, METASTATIC HEPATOCELLULAR CARCINOMA IN AN HIV/HEPATITIS B VIRUS COINFECTED PATIENT: A CASE REPORT.CASE REPORTS European Journal of Gastroenterology Papastamopoulos, Vassilios a; Charitsis, Georgios b; Lekakis, Lazaros J.Vaslamatzis, Michael M.Skoutelis, Athanasios T.B _ ABSTRACT: We present a case of an HIV-1 infected patient with history of chronic hepatitis B and chronic alcohol use without cirrhosis, who presented with aggressive hepatocellular carcinoma with multiple metastases.Chemotherapybined with use of bevacizumab (anti-vascular endothelium growth factor monoclonal antibody) was without effect and the patient succumbed to his disease within few weeks.Our knowledge, this is the first report in the English literature of bevacizumab use for metastatic hepatocellular carcinoma in HIV-infected patients.Lippincott Williams & Wilkins, Inc.2008, Lippincott Williams & Wilkins.Rights reserved.By Lippincott Williams & Wilkins.
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