среда, 4 июня 2008 г.

Carbamazepine overdose: altered mental status and unconsciousness treated with charcoal haemoperfusion and haemodialysis: case report

Contact us to report problems with: For Publishers For Researchers For Librarians CARBAMAZEPINE OVERDOSE: ALTERED MENTAL STATUS AND UNCONSCIOUSNESS TREATED WITH CHARCOAL HAEMOPERFUSION AND HAEMODIALYSIS: CASE REPORT SOURCE: , Volume 1, Number 1203, 2008-05-24 , pp.PUBLISHER: Key: - Free Content - New Content - Subscribed Content - Free Trial Content KEYWORDS: ; ; ; ; DOCUMENT TYPE: Shortmunication This feature is in beta and some links may initially be displayed as numbers instead of article titles.Any of the links will take you to the rmended articles, regardless of the display of the link.The full text article is available for purchase $34.TAX Pressing the buy now button more than once may result in multiple purchases CREDIT/DEBIT CARD INSTITUTIONAL PAYMENT ACCOUNT OR Purchase later Key: - Free Content - New Content - Subscribed Content - Free Trial Content Website 2008 Ingenta.
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вторник, 3 июня 2008 г.

What is the place of aspirin for prevention of travel related thrombosis and is there any nice guidance or other published guidance on prevention of dvt/pe during air flights?

Pilot service has been created to help members of the primary care teams of England get answers to their clinical questions.This is the first visit to the site we rmend you read "".IMPORTANT ANNOUNCEMENT: As of June 27th the NLH Q" name="updateContentForm"> What is the place of aspirin for prevention of travel related thrombosis and is there any NICE guidance or other published guidance on prevention of DVT/PE during air flights?28/May/08 ANSWER: CKS have a guideline 'DVT - advice for travellers' .Guideline (URL below) has a simply risk stratification scheme and suggested interventions based on these risks.States: _"For continuous journeys up to 6 hours, no special precautions are needed.With regard to aspirin it reports: _"Aspirin is not included as there is no evidence that it is effective in preventing travel-related deep vein thrombosis (DVT).It later expands on the above: _"WHAT EVIDENCE SUPPORTS THE USE OF ASPIRIN TO PREVENT TRAVEL-RELATED VTE?_The efficacy of aspirin has been estimated in terms of the number need to treat with aspirin to prevent one person having travel-related venous thromboembolism (VTE).Ranged from 8600 for people at high risk, to 34,000 for for people low risk of VTE ._We could find no trial of aspirin used to prevent VTE in long-distance travellers (Medline search date November 2005).REFERENCE 1) The NLH Question Answering Service aims to answer questions quickly, it is not a systematic review.You have any doubt as to the implications of this contact the Q&A Service Provider for further information.
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Courts reject two major vioxx verdicts

Reversing the verdict, the appeals court found that plaintiffs had not proved that Vioxx caused Mr.Death.Appeals court in New Jersey sharply reduced a verdict in another Vioxx case.Court ruled that the jury should not have been allowed to award punitive damages against Merck or to find that Merck hadmitted consumer fraud.Damages of $4.Were permitted, the court said.On Thursday leave lawyers for plaintiffs with just three victories, all with relatively small awards, in the nearly 20 Vioxx cases that have reached juries.Lanier, a plaintiffs' lawyer who was involved in both cases decided Thursday, criticized the decisions and promised appeals.Plaintiffs face an uphill battle.General counsel, said thepany was pleased with the rulings.In the judges and the fairness of the process has been well placed," he said.May further discourage lawyers from pursuing lawsuits against drug makers.Plaintiffs' lawyers are nervously awaiting a ruling in a case that will be heard this fall and could bar most lawsuits againstpanies for injuries said to be caused by prescription medicines approved by the .According to the government's and drug industry's argument in the Supreme Court case, the F.Not individual juries, should be responsible for evaluating the risks and benefits of a drug.Short run, Thursday's rulings will make little difference either to Merck or plaintiffs' lawyers, since the two sides have already agreed to a $4.Settlement that will largely end the Vioxx litigation.Covers about 50,000 people who have sued Merck claiming that they or their family members had heart attacks or strokes after taking Vioxx.A June 30 deadline to agree to the settlement, which will result in an average payment of roughly $100,000 a plaintiff before legal fees, or to opt out and continue their lawsuits.Opt out of the settlement if not enough plaintiffs agree to it.Mr.Said on Thursday that about 95 percent of eligible plaintiffs had agreed to the deal and that thepany was nearly certain it will go forward.A former health care investment analyst and now the managing partner of Krensavage Partners, a health care fund, said that the rulings released Thursday made him doubt the wisdom of Merck's decision last November to settle the lawsuits."Today's decisions verify Merck's initial strategy of fighting every case and raises questions about the wisdom of settling," Mr. Mr.General counsel, said thepany was satisfied that it had made the right decision in settling.And Benjamin Zipursky, a professor at Fordham Law School who has closely followed the Vioxx litigation, said Thursday's rulings did not change his opinion that Merck had been right to settle the cases.The appeals court rulings are not as positive for Merck as they may first appear, Mr.Said.Appeals court overturned the verdict on narrow factual grounds, he said, while the New Jersey court did allow for a damages award."A $4.Damages award for the plaintiff was affirmed," Mr.Said.Is a huge vindication of the plaintiff.26 cents on Thursday, closing at $38.In the Texas case, three appeals court judges reversed the verdict of a jury, throwing out the views of the plaintiffs' experts.New Jersey case, the appeals court allowed the basicpensatory damages verdict to stand, but found that the F.Pre-emption power barred the jury from awarding punitive damages.Ruled plaintiffs should not have been allowed to allege consumer fraud.TIPS To find reference information about the words used in this article, double-click on any word, phrase or name.New window will open with a dictionary definition or encyclopedia entry.COVERAGE (April 16, 2008) (February 8, 2008) (November 10, 2007) (September 7, 2007) RELATED SEARCHES Also in Real Estate: Advertisements Which movies do the Critics rmend?
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понедельник, 2 июня 2008 г.

The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke

You have forgotten your username or password, we can .My Menu Saved Items дё­ж–‡(з®ЂдЅ") дё­ж–‡(з№Ѓй«") English Deutsch н•њкµ­м–ґ ж—Ґжњ¬иЄћ Franais Espaol Ш§Щ„Ш№Ш±ШЁЩЉШ© Р СѓСЃСЃРєРёР№ Journal Article THEPARATIVE EFFECTS OF SEVOFLURANE VERSUS ISOFLURANE ON CEREBROVASCULAR CARBON DIOXIDE REACTIVITY IN PATIENTS WITH PREVIOUS STROKE Journal Publisher Springer Japan ISSN 0913-8668 (Print) 1438-8359 (Online) Issue Category Original Article DOI 10.Pages 135-139 Subject Collection SpringerLink Date Sunday, May 25, 2008 ORIGINAL ARTICLE Theparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke Yuji Kadoi1 , Shigeru Saito1 and Ken-Ichiro Takahashi2 (1) Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan (2) Department of Anesthesia, Tone Central Hospital, Gunma, Japan RECEIVED: 27 August 2007 ACCEPTED: 11 January 2008 PUBLISHED ONLINE: 25 May 2008 Abstract Purpose The use of volatile anesthetics is reportedly related to altered cerebrovascular carbon dioxide (CO2) reactivity.Examined theparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke.Twenty-four patients with previous stroke and 20 patients without previous stroke (serving as controls) were studied.With either end-tidal 1.Alveolar concentration (MAC) sevoflurane or 1.Isoflurane in 33% oxygen and 67% nitrous oxide.2.Transcranial Doppler (TCD) probe was attached to the patient's head at the right or left temporal window for continuous measurement of mean blood flow velocity in the middle cerebral artery (Vmca).Establishing baseline values of Vmca and cardiovascular hemodynamics, we increased end-tidal CO2 by decreasing the ventilatory frequency by 2-5 breathsВ·min-1.Results We found that values for absolute and relative CO2 reactivity in the sevoflurane groups were lower than those in the isoflurane groups (absolute CO2 reactivity in the sevoflurane groups: control, 3.0.Stroke, 3.Absolute CO2 reactivity in the isoflurane groups: control, 4.Previous stroke, 4.0.< 0.Isoflurane group).Were no significant differences in the values for absolute and relative CO2 reactivity between the controls and the previous-stroke patients within each of the sevoflurane and isoflurane groups.Conclusion Our findings suggest that, in patients with previous stroke, cerebrovascular CO2 reactivity under sevoflurane anesthesia was lower than that under isoflurane anesthesia.Key words Cerebrovascular CO2 reactivity - Previous stroke - Transcranial Doppler sonography - Sevoflurane - Isoflurane References secured to subscribers.Find Query Builder Close Clear Within all content Within this journal Within this issue Export this article Export this article as RIS Text В© Springer.
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Nitric oxide and l-type calcium channel influences the changes in arterial blood pressure and heart rate induced by central angiotesin ii

Antipressor action of L-Type calcium channel antagonist, nifedipine, has been studied when it was injected into the third ventricle prior to angiotensin II.Influence of nitric oxide on nifedipine antipressor action has also been studied by utilizing NW-nitro-L-arginine methyl ester (LNAME ) (40ug/0.Nitric oxide synthase inhibitor and L-arginine (20ug/0.Nitric oxide donor agent.Male Holtzman rats weighting 200-250 g, with cannulae implanted into the third ventricle were injected with angiotensin II.Produced an elevation in mean arterial pressure and a decreased in heart rate.Effects were potentiated by the prior injection of LNAME.And nifedipine blocked the effects of angiotensin II.Data showed the involvement of L-Type calcium channel and a free radical gas nitric oxide in the central control of angiotensin II-induced pressor effect.Suggested that L-Type calcium channel of the circunventricular structures of central nervous system participated in both short and long term neuronal actions of ANG II with the influence of nitrergic system.
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воскресенье, 1 июня 2008 г.

Serum anti-mullerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles.

ARTICLE LINKS: SERUM ANTI-MULLERIAN HORMONE AND ESTRADIOL LEVELS AS PREDICTORS OF OVARIAN HYPERSTIMULATION SYNDROME IN ASSISTED REPRODUCTION TECHNOLOGY CYCLES.GYNECOLOGY Obstetrical Liu, Chung-Hsien; Huang, Chuin-Chia; Wu, Yi-Ling; Shih, Yang-Tse; Ho, Hong-Nerng; Yang, Yu-Shih; Lee, Maw-Shang _ ABSTRACT: Ovarian hyperstimulation syndrome (OHSS) is a serious and sometimes a life-threateningplication of controlled ovarian stimulation (COS).Difficult to accurately predict OHSS in any particular in vitro fertilization (IVF) treatment cycle.Serum levels of anti-mullerian hormone (AMH) are closely related to the ovarian response or ovarian reserve during IVF cycles.Goal of this study was to determine how reliably the basal serum AMH level predicted OHSS in a prospective cohort of 262 IVF cycles.Women followed a long or short gonadotropin-releasing hormone (GnRH) agonist protocol, and the luteal phase was supported by human chorionic gonadotropin (hCG).Micronized progesterone was given after the serum estradiol level exceeded 3000 pg/mL or more than 15 oocytes were retrieved.Severe OHSS was noted in 8% of patients, only one of whom followed the short GnRH agonist protocol.Overall rate of clinical pregnancy was 41%.Basal serum AMH level predicted OHSS more accurately than either age or body mass index.Sensitivity was 90.Its specificity was 81.Logistic regression analysis identified basal serum AMH (odds ratio, 1.= 0.The serum estradiol level on the day of hCG treatment (odds ratio, 1.0.Significant predictors of OHSS.Logistic regression analysis, the only significant factor predicting clinical pregnancy was age (odds ratio, 0.= 0.Basal serum AMH did not effectively predict clinical pregnancy.Basal serum AMH reliably predicts OHSS and may be used to ensure that patients with high levels receive a mild, patient-friendly protocol for ovarian stimulation.Lippincott Williams & Wilkins, Inc.2008, Lippincott Williams & Wilkins.Rights reserved.By Lippincott Williams & Wilkins.
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Insulin boost for early diabetes

380 patients in the Lancet trial were later managed with the standard diet and exercise regime.Diabetes UK said the approach may be useful for some patients.A second study also published in The Lancet found taking part in diet and exercise programmes for six years can prevent or delay diabetes for up to 14 years.There are 2.Diabetes in the UK, the vast majority of whom have type 2 diabetes - where the body does not produce enough insulin or the insulin that is produced does not work properly.THE RESEARCH SHOWS THAT CONSIDERING USING INSULIN EARLY WHEN PEOPLE ARE FIRST DIAGNOSED WITH TYPE 2 DIABETES MIGHT BE AN ADDITIONAL WAY TO ACHIEVE GOOD DIABETES MANAGEMENT Pav Pank, Diabetes UK Normal management of the condition includes making lifestyle changes, with the addition of medication as necessary.However, previous research has suggested that initial intensive therapy to get blood sugar levels under control could change or delay the natural course of the disease.TREATMENT BOOST Patients aged 25 to 70 taking part in the trial were given an infusion of insulin, daily insulin injections or oral anti-diabetic tablets.The treatment was only given for two weeks after normal blood glucose levels were achieved.Most of those given insulin were able to meet blood glucose targets in four to five dayspared with nine days in those given oral drugs.After a year, 51% of patients given an insulin infusion and 45% of those given insulin injections had maintained their good blood glucose levels by sticking to a diet and exercise programme.But only 27% of those who had initially been treated with oral drugs still had good blood glucose control.The researchers reported that the early insulin treatment seemed to have restored the function of insulin-producing beta cells in the body.Tests showed the cells had a better response to insulin after treatment and the effect was sustained after a year.Study leader, Professor Jianping Weng, said good diabetes control, especially early intensive blood sugar control, can eliminate the damage caused by high blood sugar levels and rescue injured beta-cells.Pav Pank, care advisor at Diabetes UK, said achieving good diabetes control is key to diabetes management and also helps prevent people with the condition from developing life-threateningplications such as heart disease, stroke, kidney disease, amputation and blindness."The research shows that considering using insulin early when people are first diagnosed with type 2 diabetes might be an additional way to achieve good diabetes management."Nevertheless decisions about treatment need to be made on an individual basis for each patient.Professor Rury Holman, head of the Diabetes Trial Unit at Oxford University, said the research was "important" but more information was needed on different measures of diabetes control before a change in practice could be advocated.WITH: SEE ALSO 07 May 08 Health 18 Apr 08 Health 25 Feb 08 Health 11 Jan 08 Health 25 Oct 07 Health RELATED INTERNET LINKS The BBC is not responsible for the content of external internet sites E-MAILED READ WATCHED/LISTENED FEATURES, VIEWS, ANALYSIS Band member David Marks tells of his fight with hepatitis Inquest evidence highlights aircraft design faults Why a brisk stroll could be just what the doctor ordered EXPLORE THE BBC POPULAR LINKS BBC LINKS A TO F BBC LINKS H TO L BBC LINKS M TO SC BBC LINKS SP TO W SITE LINKS BBC LINKS MMVIII The BBC is not responsible for the content of external internet sites.THIS PAGE IS BEST VIEWED IN AN UP-TO-DATE WEB BROWSER WITH STYLE SHEETS (CSS) ENABLED.
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