Study of 581 African-American and Caucasian women with and without non-small-cell lung cancer (NSCLC) indicates that regular use of aspirin reduces the risk for the disease by a significant 34%.Studies have suggested that aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) could decrease the risk for NSCLC, while others have reported conflicting results, say Alison Van Dyke (Wayne State University School of Medicine, Detroit, Michigan, USA) and colleagues.Poor 5-year survival rate of lung cancer patients, finding a means of preventing lung cancer is imperative," says the team.Smoking cessation, there are no known methods for preventing lung cancer.Participants, who were aged 18-74 years and diagnosed with primary NSCLC between November 2001 and October 2005, werepared with 541 population-based controls.And co-workers found that the reduction in risk for NSCLC held after adjustment for body mass index (BMI), family history of lung cancer, history of chronic obstructive lung disease, arthritis, and cardiovascular disease.Protection increased significantly with duration of use.The reduction in NSCLC with regular use of aspirin was confined to Caucasian women (odds ratio =0.Women aged 55-64 years (OR=0.Regular use of baby aspirin and use of acetaminophen and NSAIDs were not significantly associated with the risk for lung cancer in adjusted analyses.Read more Paracetamol (acetaminophen) esters of some non-steroidal anti-inflammatory carboxylic acids as mutual prodrugs with improved therapeutic index
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