You have forgotten your username or password, we can .My Menu Saved Items дёж–‡(з®ЂдЅ") дёж–‡(з№Ѓй«") English Deutsch н•њкµм–ґ ж—Ґжњ¬иЄћ Franais Espaol Ш§Щ„Ш№Ш±ШЁЩЉШ© Р СѓСЃСЃРєРёР№ Journal Article THEPARATIVE EFFECTS OF SEVOFLURANE VERSUS ISOFLURANE ON CEREBROVASCULAR CARBON DIOXIDE REACTIVITY IN PATIENTS WITH PREVIOUS STROKE Journal Publisher Springer Japan ISSN 0913-8668 (Print) 1438-8359 (Online) Issue Category Original Article DOI 10.Pages 135-139 Subject Collection SpringerLink Date Sunday, May 25, 2008 ORIGINAL ARTICLE Theparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke Yuji Kadoi1 , Shigeru Saito1 and Ken-Ichiro Takahashi2 (1) Department of Anesthesiology, Gunma University Hospital, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan (2) Department of Anesthesia, Tone Central Hospital, Gunma, Japan RECEIVED: 27 August 2007 ACCEPTED: 11 January 2008 PUBLISHED ONLINE: 25 May 2008 Abstract Purpose The use of volatile anesthetics is reportedly related to altered cerebrovascular carbon dioxide (CO2) reactivity.Examined theparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke.Twenty-four patients with previous stroke and 20 patients without previous stroke (serving as controls) were studied.With either end-tidal 1.Alveolar concentration (MAC) sevoflurane or 1.Isoflurane in 33% oxygen and 67% nitrous oxide.2.Transcranial Doppler (TCD) probe was attached to the patient's head at the right or left temporal window for continuous measurement of mean blood flow velocity in the middle cerebral artery (Vmca).Establishing baseline values of Vmca and cardiovascular hemodynamics, we increased end-tidal CO2 by decreasing the ventilatory frequency by 2-5 breathsВ·min-1.Results We found that values for absolute and relative CO2 reactivity in the sevoflurane groups were lower than those in the isoflurane groups (absolute CO2 reactivity in the sevoflurane groups: control, 3.0.Stroke, 3.Absolute CO2 reactivity in the isoflurane groups: control, 4.Previous stroke, 4.0.< 0.Isoflurane group).Were no significant differences in the values for absolute and relative CO2 reactivity between the controls and the previous-stroke patients within each of the sevoflurane and isoflurane groups.Conclusion Our findings suggest that, in patients with previous stroke, cerebrovascular CO2 reactivity under sevoflurane anesthesia was lower than that under isoflurane anesthesia.Key words Cerebrovascular CO2 reactivity - Previous stroke - Transcranial Doppler sonography - Sevoflurane - Isoflurane References secured to subscribers.Find Query Builder Close Clear Within all content Within this journal Within this issue Export this article Export this article as RIS Text В© Springer.Read more Late treatment with letrozole can reduce breast cancer recurrence risk
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