четверг, 6 марта 2008 г.

A dose–response relationship research on botulinum toxin type a local intramuscular injections of lower extremity spasticity in children with cerebral palsy

You have forgotten your username or password, we can .My Menu Saved Items дё­ж–‡(з®ЂдЅ") дё­ж–‡(з№Ѓй«") English Deutsch н•њкµ­м–ґ ж—Ґжњ¬иЄћ Franais Espaol Ш§Щ„Ш№Ш±ШЁЩЉШ© Р СѓСЃСЃРєРёР№ Journal Article A doseвЂ"response relationship research on botulinum toxin type A local intramuscular injections of lower extremity spasticity in children with cerebral palsy Journal Publisher Springer Berlin / Heidelberg ISSN 0256-7040 (Print) 1433-0350 (Online) Status Category Briefmunication DOI 10.Subject Collection SpringerLink Date Saturday, February 23, 2008 BRIEFMUNICATION A dose-response relationship research on botulinum toxin type A local intramuscular injections of lower extremity spasticity in children with cerebral palsy Yajie Wang1, 2 and Baoqin Gao1, 2 (1) Department of Pediatrics, Beijing TianTan Hospital, Beijing, 100050, China (2) Capital University of Medical Science, Beijing, 100050, China RECEIVED: 28 November 2007 PUBLISHED ONLINE: 23 February 2008 Abstract Objectives To observe the dose-response relationship of intramuscular injections of botulinum toxin A (BTX-A) in the spastic cerebral palsy.Methods One hundred fifty cases (age between 2 and 12 years) were randomly divided into three groups.Patients were injected with different dose of BTX-A.Movement function was evaluated with modified Ashworth scale (MAS) and physician's rating scale (PRS) at entry and 1 month after injection.Analyses were conducted with one-way analysis of variance and __ 2 test.Results The evaluation of MAS and PRS revealed a significant increase of movement function.Statistically significant differences of the side effects among three groups could be demonstrated.Conclusions The study suggested that the movement function was more significantly improved with relatively higher dose of BTX-A, which was safe and effective.Keywords Botulinum toxin A - Cerebral palsy - Dose - Response - Child - Spasticity YAJIE WANG EMAIL: References secured to subscribers.Find Query Builder Close Clear Within all content Within this journal Export this article Export this article as RIS Text Text PDF The size of this document is 75.Although it may be a lengthier download, this is the most authoritative online format.HTML This offers the quickest access for ease of browsing.Note that some scientific and mathematical characters may not render as precisely as in PDF versions.В© Springer.
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