A case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole

You have forgotten your username or password, we can .My Menu Saved Items дё­ж–‡(з®ЂдЅ") дё­ж–‡(з№Ѓй«") English Deutsch н•њкµ­м–ґ ж—Ґжњ¬иЄћ Franais Espaol Ш§Щ„Ш№Ш±ШЁЩЉШ© Р СѓСЃСЃРєРёР№ Journal Article A CASE OF BENIGN METASTASIZING LEIOMYOMA TREATED BY SURGICAL CASTRATION FOLLOWED BY AN AROMATASE INHIBITOR, ANASTROZOLE Journal Publisher Springer Berlin / Heidelberg ISSN 0932-0067 (Print) 1432-0711 (Online) Category Case Report DOI 10.Subject Collection SpringerLink Date Wednesday, June 04, 2008 CASE REPORT A case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole Kaei Nasu1 , Akitoshi Tsuno1, Noriyuki Takai1 and Hisashi Narahara1 (1) Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu-shi, Oita 879-5593, Japan RECEIVED: 3 April 2008 ACCEPTED: 20 May 2008 PUBLISHED ONLINE: 4 June 2008 Abstract Background Benign metastasizing leiomyoma (BML) is a rare disease most often located in the lungs of women with a history of surgery for benign leiomyoma of the uterus.Therapy for BML, has not been established.Report here an additional case of BML in the lung that was successfully treated with surgical castration followed by hormonal therapy with anastrozole, an aromatase inhibitor.Case A 46-year-old primigravid Japanese woman was admitted to our hospital for investigation of multiple pulmonary nodules found on a routine chest X-ray.The age of 36, she had undergone myomectomy for uterine myomas.Gynecological examination, her uterus, was enlarged to the size of a child's head.Total hysterectomy, bilateral salpingo-oophorectomy, and thracoscopic biopsy of pulmonary nodules were performed.The lung nodules were diagnosed as BML.Oral anastrozole was started.Patient is alive and the size of the pulmonary nodules was stable, 15 months following the surgery.Conclusion In addition to castration by bilateral oophorectomy or gonadotropin-releasing hormone agonist, the use of aromatase inhibitor is one of the treatment options for the further suppression of peripheral estrogen production in these patients.Benign metastasizing leiomyoma - Bilateral oophorectomy - Aromatase inhibitor KAEI NASU EMAIL: References secured to subscribers.Find Query Builder Close Clear Within all content Within this journal Export this article Export this article as RIS Text В© Springer.
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