ARTICLE LINKS: AN OPEN-LABEL PILOT STUDY TO EVALUATE THE EFFICACY OF SILDENAFIL CITRATE IN MIDDLE-AGED MEN WITH LATE-ONSET DYSTHYMIA.BRIEF REPORT Journal of Nervous Seidman, Stuart N.++ _ ABSTRACT: Late onset dysthymic disorder (DD) in middle-aged and elderly men responds poorly to established antidepressants.Studies noted an improvement in mood apanying sildenafil citrate treatment for erectile dysfunction.Sought to evaluate whether sildenafil's mood effects were independent of the effect on erectile function.6-week open label study was conducted with 20 male participants, aged 41-60 who were diagnosed with DD and who had normal erectile function.With sildenafil citrate 25 mg per day for 6 weeks.Primary oue measure was the 21-item Hamilton Depression Rating Scale.And sexual symptoms were also evaluated using self-report questionnaires.With sildenafil resulted in a significant reduction in Hamilton Depression Rating Scale mean scores: from 14.3.Baseline to 6.Read more Bisoprolol: acute generalised exanthematous pustulosis (first report) in an elderly patient: case report
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