Stephen McMahon (George Institute viagra online pharmacy for International Health, University of Sydney, New South Wales, Australia) said that such an approach of simply adding a fixed-dosebination therapy irrespective of starting BP, and without aiming for specific BP goals, would provide a simple and effective way to greatly reduce the burden of diabetes-related cardiovascular disease.Results at the European Society of Cardiology Annual Congress in Vienna, Austria alert black joke market viagra , McMahon noted: "While much attention has been placed on achieving glucose control in diabetes patients, it is less well recognized that high blood pressure is one of the critical determinants of vascularplications.Patients do not have hypertension, he explained, but data from the UK Prospective Diabetes Study (UKPDS) suggested that they would also benefit from blood-pressure lowering.Study, the associations between online store viagra systolic blood press (SBP) lowering and reductions in myocardial infarction and microvascular endpoints persisted well below the average SBP level of 145 mmHg achieved with intervention.(Action in Diabetes and Vascular Disease: preterax and diamicron-MR Controlled cheapest viagra Evaluation) trial enrolled 11,140 Type 2 diabetes patients with either a history of major cardiovascular disease or at least one other viagra risk factor for cardiovascular disease.Received the fixedbination tablet containing perindopril 2 mg and indapamide 0.Daily for the 6-week pre-randomization run-in period.Patients continued to take their usual background treatment, except for any angiotensin converting enzyme (ACE) inhibitor other than perindopril, and any other thiazide diuretic.ACE inhibitor was substituted for perindopril.Then randomly assigned to receive the same fixed-dosebination or placebo and at 3 months buy in uk viagra thebination dose was doubled to perindopril 4 mg and indapamide 1.4.Of follow-up,bination-treated patients' average SBP and DBP levels were 5.And 2.Lower, respectively, than placebo-treated patients' levels.Levels, at an average of 135 mHg inbination-treated patients and 140 mmHg in placebo-treated patients, were lower than the corresponding viagra side effects 145 mmHg and 155 mmHg in the intervention and placebo arms of UKPDS, McMahon noted.Current study therefore included patients with a lower BP range than has previously been examined.Simultaneously published advance online by _The Lancet_, show that the ACE-inhibitor plus diureticbination reduced the risk for all-cause mortality by 14% relative to placebo (p=0.This was driven by a reduction in cardiovascular deaths, at a relative risk reduction of 18% (p=0.Was also associated with a 9% relative risk reduction for thebined oue of any major macro- or microvascular event (p=0.However, separate reductions in macrovascular and microvascular events were not independently significant.Significantly reduced with the perindopril plus indapamidebination were coronary heart disease, by 14%, and renal disease, by 21%.The lack of independent effect on macrovascular events despite a significant reduction in coronary heart disease could be attributed in part to a low cerebrovascular event rate, and to the relatively modest degree of BP reduction.Similar benefits were seen in patients with and without hypertension at baseline, as well as in the presence or absence of treatment with: ACE inhibitors and other BP lowering drugs; statins and other lipid-lowering drugs; and aspirin and other antiplatelet viagra sample cheapest price viagra drugs.Investigators say that, in absolute terms canada online viagra , the results mean one death could be avoided for every 79 patients treated with the fixedbination of perindopril and indapamide for 5 years.
Read more Needles in, wrinkles out
Get more Ranbaxy receives tentative fda approval for fexofenadine hydrochloride tablets
