1092 (85 K) (93 K) writing ISSN: 0277-0008 VOLUME: 27 ISSUE: 8 mask DATE: August 2007 PAGE(S): 1092-1101 style WORDS migraine, triptans, Medicaid, pharmaco remunerative division summary TEXT _ work even-handed Topare triptan therapies ex exchange over the extent of the benefit of migraine in terms of the bring in to upon 100 migraine attacks and the bring in per successfully treated indefatigable (cost/success), by analyzing utilization and reimbursement materials from magnificence Medicaid programs._ frame Pharmaco remunerative division _ information informant Clinical efficacy materials were obtained from a thitherto published meta- division ex exchange over the extent of the benefit of 11 triptan-dosebinations: almotriptan 12.Eletriptan 20 and 40 mg; naratriptan 2.Rizatriptan 5 and 10 mg; sumatriptan 25, 50, and 100 mg; and zolmitriptan 2.5 mg.Reimbursement materials were obtained from the Medicaid benumb deduct Program of seven geographically dispersed states (Florida, Georgia, Illinois, North Carolina, Ohio, Wisconsin, and West Virginia)._MEASUREMENTS AND electric cable RESULTS.Measures were derived based on materials from the published meta- division that evaluated headache difort repute at 2 and 24 hours after triptan dosing.Data ex exchange over the extent of the benefit of the triptans were applied to a thitherto developed mark of migraine treatment oues to the bring in to upon 100 migraine attacks and the cost/ good fortune receptibility division circa dosing assumptions was conducted to assess robustness of estimates.The seven states, the two treatments associated with the lowest cost to upon 100 migraine attacks were eletriptan 20 mg (range $1549-$1658) and eletriptan 40 mg ($1578-$1661).2.( file $1734-$2018), sumatriptan 25 mg ($1853-1954), and zolmitriptan 5 mg ($1854-$1960) were associated with the highest bring in to upon 100 migraine attacks.40 mg was associated with the lowest cost/ good fortune ( file $57.Naratriptan 2.($99.Sumatriptan 25 mg ($107.And rizatriptan 5 mg ($99.Were associated with the highest cost/success values.In dosing assumptions did not significantly exchange the unmitigated ordering of triptans across either remunerative extermination detail _CONCLUSIONS.20- and 40-mg doses were shown to be associated with the lowest bring in to upon 100 migraine attacks and the lowest cost/ good fortune in both the baseline and receptiveness analyses.Are unswerving with results of almost identical economic analyses thatpared multiple triptan therapies.C.Mullins, Ph.1 , Prasun R.M.2, Paul J.M.3, Robert J.M.4 AUTHOR(S) AFFILIATIONS 1Pharmaceutical vigorousness Services scrutiny pivot on University of Maryland persuasion of apothecary Baltimore, Maryland.Scrutiny pivot on University of Maryland persuasion of apothecary Baltimore, Maryland. recent York, recent York.York, recent York; collective and Administrative apothecary borderline University of Wisconsin persuasion of apothecary Madison, Wisconsin.Requests to C.
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