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The expression profile of micro-rna in endometrium and endometriosis and the influence of ovarian steroids on their expression

MOL.REPROD.ACCESS ORIGINALLY PUBLISHED ONLINE ON AUGUST 31, 2007 Molecular Human Reproduction 2007 13(11):797-806; doi:10.This Article OA All Versions of this Article: 13/11/797 _most recent_ Services Google free generic shipping viagra Scholar PubMed (c) The Author 2007.Oxford University Press on behalf of the European Society of Human Reproduction and female viagra cream viagra online Embryology.Reserved.Permissions, please email: journals.The online version of this article has been published under an open followup post viagra access model.Are entitled to use, reproduce, disseminate, or display the open access version of this article for nonmercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation viagra sales details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated.Re-use, please contact journals.THE EXPRESSION PROFILE OF MICRO-RNA IN ENDOMETRIUM AND ENDOMETRIOSIS AND THE INFLUENCE OF OVARIAN viagra shop STEROIDS ON THEIR EXPRESSION QUN PAN, XIAOPING LUO, TANNAZ TOLOUBEYDOKHTI AND NASSER CHEGINI1 Department of Obstetrics/Gynecology, University of Florida, Box 100294, Gainesville, FL 32610, USA 1 Correspondence address.+1-352-273-7566; Fax: +1-352-392-6994; E-mail: cheginin{at}obgyn.MicroRNAs (miRNAs), through mRNA degradation or repression, act as key regulator of gene expression.Aim was to identify specific miRNAs that are expressed in endometrium of women with and without endometriosis.Profiled the expression of 287 miRNAs in paired eutopic and ectopic endometrium and isolated endometrial cells using microarray and validated the expression of selected miRNAs using real-time PCR.The basis of global normalization, 65 of these miRNAs were better cialis levitra viagra which identified to be expressed above the threshold levels set during the analysis in the endometrium of women without endometriosis with a progressive decline in expression in paired eutopic and ectopic endometrium.(ANOVA) identified 48 of these miRNAs as differentially expressed among these tissues and 32 miRNAs between isolated endometrial stromal cell (ESC) and glandular epithelial cell (GEC) (_P_ < 0.The expression of hsa-miR20a, hsa-miR21, hsa-miR26a, hsa-miR18a, hsa-miR206, hsa-miR181a and hsa-miR142-5p, predicted to target many genes, including TGF-R2, ER_, ER and PR, respectively, was validated in these tissues and cells using real-time PCR.
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