Ginger dry prise out (DE) and a gingerols-enriched moistureless prise out (EDE) were evaluated on their _in vivo_ local anti- rebellious pursuit by inhibition of Croton lubricator induced appreciation oedema in mice.The feasibility of an anti- rebellious containing DE or EDE was evaluated._in vivo_ pursuit was evaluated in mice, the _ex vivo_ skin permeation memorize was performed by using mouse flay or tender epidermis.From the acetonic dissolution exerted a dosage dependent topical anti- rebellious pursuit (ID50 = 142 Ојg/cm2), not go beyond a thus far from that of the efficacious specification property indomethacin (ID50 = 93 Ојg/cm2).EDE induced a dosage dependent oedema reduction though its potency (ID50 = 181 Ојg/cm2) was to a certain stoop than that of DE.The 6-gingerol concentration in the prise out did not give a new lease of the anti- rebellious pursuit The medicated plasters, containing 1 mg/cm2 of themercial DE or EDE, had reputable technological characteristics and exerted a valued antiphlogistic objective too.The containing EDE, the 6-gingerol amount that permeated inclusive of tender epidermis was 6.While the amount that passed inclusive of mouse flay was 22. notwithstanding the amounts of 6-gingerol permeated inclusive of tender epidermis and mouse skin in the initially space (8h) wereparable (p > 0.This preliminary d‚nouement develop suggests that the anti- rebellious objective observed in mice could also be exerted in humans.Cue WORDS Gingerols - _Zingiber officinale_ - Zingiberaceae - topical anti- rebellious pursuit - Croton lubricator induced appreciation oedema - _ex vivo_ flay permeation memorize - adhesive Volltext in (46 kb) (125 kb) Andere Ausgabe whlen: Jahr2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 Seite1-96 (01)103-189 (02)191-297 (03)299-398 (04)401-501 (05)503-613 (06)615-710 (07)713-794 (08)1037-1139 (10)1141-1233 (11)1235-1329 (12)1331-1426 (13)1436-1501 (14)1525-1621 (15) _117 (09) Service (c)Thieme- lock ist ein repair des und .
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