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Is there any evidence for differences in efficacy between topical nsaids? are there any studies comparing topical diclofenac (1%) gel with ibuprofen gel?

NLH Question Answering Service > Primary Care Question Answering Service Search info medical viagra Site Wee to the buying viagra board message viagra NLH's Primary Care Question Answering Service.Pilot service has been created to help members of the primary care teams of England get answers to their clinical questions.This is the first visit to the site we rmend you read "".By speciality MOST RECENT QUESTIONS: (Please click on a question for viagra use the answer) Is there any evidence for differences in efficacy between topical free pill viagra NSAIDs?There any studiesparing topical diclofenac viagra sample pack (1%) gel with ibuprofen gel?18/Dec/07 ANSWER: We searched the TRIP, Cochrane and Medline databases but found no head-to-head studiesparing diclofenac gel (1%) to ibuprofen gel.The CKS guideline on osteoarthritis notes: "What evidence supports the use of topical NSAIDS?Review has found that topical NSAIDs were effective and safe in treating in people with chronic musculoskeletal pain for 2 weeks .O Limitations included the short duration sale viagra of the trials generic online viagra and that no single preparation could be shown to be better than can woman take viagra another.A Bandolier on line prescription viagra review on the use of topical NSAIDs for chronic musculoskeletal pain, published in 2004, concludes: _"Clinical bottom cheapest online viagra line: Topical NSAIDs were clearly better than placebo in chronic musculoskeletal pain, with an NNT of 4.To 5.The best trials.Were generally of short duration, and no single preparation could be shown to be better than another.Study showed oral NSAID to be better than topical NSAID.A second online viagra sales review by Bandolier on topical NSAIDS, this time focusing on the treatment of strains and sprains free prescription sample viagra found: "Topical NSAIDS for strains and sprains Clinical bottom line: Topical NSAID was significantly better than placebo in 19 of the 26 trials, with a pooled relative benefit of 1.1.NNT of 3.To 4.Placebo for the oue of half pain relief at seven days.Was significantly better than all other topical NSAIDs.The full text of the article contains a tableparing the efficacy of five topical NSAIDs with their respective NNTs.A search in the Medline database identified the following two studies on topical NSAIDs.Abstracts of these articles read: _"…PATIENTS: Outpatients aged 18-70 years diagnosed for painful benign sport-related soft-tissue injury (sprains, strains and contusions within the prior 48 h), randomised to either ketoprofen patch 100 mg once daily (n = 114) or diclofenac gel 2-4 g three times daily (n = 109).7-14 days of topical non-steroidal anti-inflammatory drugs treatment to assess the pain intensity changes (daily activities and spontaneous at rest) in a daily diary (100-mm Visual Analogue Scale (VAS)).Oue measurement: Pain intensity (VAS)._RESULTS: The ketoprofen patch was not inferior to diclofenac gel in reducing the baseline pain during daily activities (difference of -1.In favour of ketoprofen patch, 95% CI (-5.3.The baseline VAS 79%.Patch presented also a higher cure rate (64%) than diclofenac gel (46%) at day 7 (p = 0.Patient opinions about the treatmentfort (pharmaceutical shape, application and dosage) were also statistically higher for the ketoprofen patch (>80% of the patients rated as good or excellent the patch removal and skin adherence).Ketoprofen patches are effective and safe pain relievers for the treatment of sports injury pain with advantagespared with diclofenac gel.Russo et alpared the effect of sodium naproxen to diclofenac for the control of anterior chamber inflammation following uplicated cataract surgery: "_A total of 328 patients were enrolled in a prospective, randomized, double-masked, parallel-group, active-controlled study.Inflammation (ACI) was evaluated as the primary efficacy parameter.Patients with moderate inflammation (ACI score of < or =4) the day after surgery were randomized and treated with NSAIDs.Novel topical formulation containing 0.Naproxen waspared with 0.Both were administered three times a day for 14 consecutive days.Was measured after 7 and 14 days by using slit-lamp biomicroscopy.Parameters were also evaluated at the same time.Both treatments were equally effective in controlling postsurgical inflammation.Statistically significant differences between treatment groups were observed for the safety variables.Adverse events (AEs) occurred during the course of the study.Frequent AE reported with naproxen was eye redness.Effectively be used without concurrent administration 1 buy viagra of corticosteroids to control postoperative inflammation after uplicated cataract surgery.Addition, naproxen ophthalmic solution may be considered a suitable alternative to the currently buy cheapest online place viagra available NSAIDs.1.Osteoarthritis.2.Topical NSAIDs for chronic musculoskeletal pain. Bandolier.NSAIDs for strains and sprains.4.F, Cobiбn C, Jimйnez JF et al.TDS patch versus diclofenac gel: efficacy and tolerability in benign sport related soft-tissue injuries.J Sports Med.2006 Nov 30.5.P, Papa V, Russo S et al.Nonsteroidal anti-inflammatory drugs in uplicated cataract surgery: effect of sodium naproxen.J Ophthalmol.() The NLH Question Answering Service aims to answer questions quickly, it is not a systematic review.You have any doubt as to the implications of this contact the Q&A Service Provider for further information.
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