суббота, 16 февраля 2008 г.

Consumption of vegetables alters morning urinary 6-sulfatoxymelatonin concentration

1600-079X. Abstract CONSUMPTION OF VEGETABLES ALTERS MORNING URINARY 6-SULFATOXYMELATONIN CONCENTRATION Shino Oba, Kozue Nakamura, Yukari Sahashi, Atsuhiko Hattori and Chisato Nagata 1Department of Prevention for Lifestyle-related Diseases, Gifu University Graduate School of Medicine, Gifu, Japan; 2Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan; 3Department of Biology, College of Liberal Arts and Sciences, Tokyo Medical and Dental University, Chiba, Japan Address reprint requests to Chisato Nagata, Professor of Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, Gifu 501-1194, Japan.ABSTRACT Abstract: Melatonin, which is contained in certain vegetables, may have an influence on circulatory melatonin concentrations.Study examined the effects of the consumption of vegetables on 6-sulfatoxymelatonin concentrations in morning urine.Women aged 24-55 were recruited through a city public health center in Japan.Women randomly allocated to the intervention group were requested to consume high amounts of six selected vegetables, with a target of 350 g/day for 65 days, while those in the control group were asked to avoid the same six vegetables during the same period.Morning urine was collected before and at the end of the intervention period, and creatinine-adjusted 6-sulfatoxymelatonin concentrations were measured.The end of the intervention period, daily mean intake of melatonin from the six vegetables was 1288.In the intervention group and 5.In the control group.The intervention group, the mean concentration of 6-sulfatoxymelatonin changed from 48.Ng/mg creatinine to 49.CI: 42.Ng/mg creatinine across the intervention period.The control group, the mean concentration of 6-sulfatoxymelatonin changed from 55.CI: 48.Ng/mg creatinine to 50.CI: 44.Ng/mg creatinine across the intervention period.Of the two groups with regard to the changes in the 6-sulfatoxymelatonin concentrations across the intervention period showed a significant difference (_P_ = 0.
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