"confirm the discrepancy between dietary intervention studies showing reasonable BP lowering effects and intervention studies with abination of minerals or vitamins showing no effect," say the authors.The need to explore potential BP lowering effects of vitamins and minerals consumed in "natural matrices" in the diet rather than as supplements, they add.Research letter to the _Journal of Human Hypertension_, P de Leeuw (University Hospital Maastricht, The Netherlands) and colleagues explain that dietary intervention studies have shown impressive reductions in BP, probably due in part to the mineral and vitaminponents of such diets.Interventions withbinations of either minerals or vitamins have provided mixed results.Current study, the researchers tested the BP lowering effect of abination of minerals and vitamins.Randomly assigned 124 adults with untreated mild hypertension to take a supplemented skimmed milk drink or a placebo drink daily for 8 weeks.Was supplemented with 446 mg calcium, 100 mg magnesium, 40 Вµg selenium, 180 mg vitamin C, 30 mg vitamin E and tocopherol equivalents, and either 1500 mg (high-K) or 750 mg (low-K) potassium per serving.Of the study, office systolic BP had decreased by 4.And 5.Baseline in the low-K supplement, high-K supplement, and placebo groups, respectively.Differences in BP reduction among groups were nonsignificant.Office diastolic BP, pulse pressure, 24-hour systolic BP, 24-hour diastolic BP, and heart rate over the 8 weeks did not differ among the three groups either."are in contrast with many studies addressing interventions with the individualponents," the authors write.Note that the doses of the individual minerals and vitamins may have been too low, and thatbinations of vitamins and minerals may counter the effects of the individualponents.Read more Merck agrees to settle 27,000 vioxx lawsuits for $4.85b
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