S.D.A.Potential benefits of early addition of rosiglitazone inbination with glimepiride in the treatment of type 2 diabetes Diabetes, Obesity and Metabolism (OnlineEarly Articles).1463-1326. Abstract ORIGINAL ARTICLE POTENTIAL BENEFITS OF EARLY ADDITION OF ROSIGLITAZONE INBINATION WITH GLIMEPIRIDE IN THE TREATMENT OF TYPE 2 DIABETES J.Diabetes and Endocrine Center at Medical City, Dallas, TX, USADr J.Diabetes and Endocrine Center at Medical City, Dallas, TX 75390, USA.Juliorosenstock@dallasdiabetes H.S.K.And A.1Dallas Diabetes and Endocrine Center at Medical City, Dallas, TX, USA 2Daiichi Sankyo Pharma Development, Edison, NJ, USA 3Diabetes-Centre Quakenbrck, Christliches Krankenhaus, Quakenbrck, Germany 4GlaxoSmithKline, Mnchen, Germany 5Abteilung Innere Medizin I, Medizinische Klinik, Universittsklinikum Heidelberg, Heidelberg, Germany Dr J.Dallas Diabetes and Endocrine Center at Medical City, Dallas, TX 75390, USA.ABSTRACT Aim: To assess the efficacy and tolerability of earlybination therapy with rosiglitazone (RSG) and glimepiride (GLIM) vs.Monotherapy in patients with type 2 diabetes mellitus (T2DM).For the addition of RSG inbination with GLIM were evaluated with data from two randomized, double-blind, placebo (PBO)-controlled studies.A - addition of RSG (4 or 8 mg) or PBO to continued GLIM 3 mg once daily; study B - addition of low-dose RSG (4 mg) prior to uptitration of GLIM (from 2 to 4 mg) vs.Uptitration of GLIM (from 2 to 8 mg).A reported significant reductions in fasting plasma glucose (FPG) from baseline to week 26 with the addition of both 4 and 8 mg RSG to GLIM 3 mg .Were no significant changes with GLIM monotherapy in either study.Effects of RSG + GLIM on insulin sensitivity, -cell function and cardiovascular disease biomarkers were also observed.Read more Dual infection with polyomavirus bk and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient
Get more Ezetimibe treatment in hypercholesterolemic kidney transplant patients is safe and effective and reduces the decline of renal allograft function: a pilot study
