воскресенье, 3 февраля 2008 г.

New azetidinone cholesterol absorption inhibitors

Pages 791-797 (doi:10.791) stylish azetidinone cholesterol absorption inhibitorsXu Bai PhDProfessor and Jilin University, The Center forbinatorial Chemistry and cure idea 75 Haiwai row Changchun, Jilin 130012, P.China +86 431 85188955; +86 431 85188900; Since their inaugural detection azetidinones secure been extensively contrived as efficacious cholesterol absorption inhibitors.The ahead in- merit and no greater than in the clinics either as a monotherapy or inbination with statins since treatment of hypercholesterolemia.Current empathy of Niemann-Pick C1-like 1 protein in the brush trimming membrane of the insignificant intestine as a imaginable molecular target has opened the door since the plan and amalgamation of new anticholesterol drugs.
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