воскресенье, 6 января 2008 г.

Celecoxib: a review of its use in the management of arthritis and acute pain

Or acquaintance us to bang problems with: through despite Publishers through despite Researchers through despite Librarians CELECOXIB: A review article OF ITS despise IN THE manipulation OF ARTHRITIS AND keen affliction AUTHORS: Frampton, James E.M.SOURCE: , 67, numbers 16, 2007 , pp. Key: - casual delighted - remodelled delighted - Subscribed delighted - casual tentative delighted ABSTRACT: Celecoxib (Celebrex(R)), the extraordinary cyclo-oxygenase (COX) 2- eclectic inhibitor (coxib) to be introduced into clinical way has been to hand in return the duration of a decade.Is approved in inseparable or more countries worldwide in return the duration of the remedy of the signs and symptoms of osteoarthritis (OA), rheumatoid arthritis (RA), minor rheumatoid arthritis (in patients superannuated 2 years) and ankylosing spondylitis (AS), the directing of critical spasm in adults, the treatment of primary dysmenorrhoea and the reduction in the mob of adenomatous colorectal polyps in familial adenomatous polyposis.An functioning and valuable altenative to nonselective NSAIDs in the treatment of critical or lingering musculoskeletal spasm In the latter environs it offers the in the offing of improved gastrointestinal (GI) tolerability and, in patients not winsome aspirin in return the duration of cardioprophylaxis, a GI shelter service better Currently available testify of an developing in cardiovascular (CV) hazard with celecoxib is inconsistent; any developing in hazard is right to be puny and similar to that with non eclectic NSAIDs.With all NSAIDs, the potential GI, CV and renal risks of celecoxib be required to be weighed against the concealed benefits in each individual; it is a enlightened select for patients at behold in the front CV hazard who be missing NSAID cure primarily those at increased hazard of NSAID-induced GI toxicity, but also those unresponsive to, or unforbearing of, other NSAIDs.Selected, celecoxib, like all NSAIDs, should be reach-me-down at the lowest effective administer in return the duration of the shortest tenable duration.KEYWORDS: ; ; ; report TYPE: check in article AFFILIATIONS: 1: Wolters Kluwer vigorousness Adis, Auckland, New Zealand, an position statement function of Wolters Kluwer vigorousness Conshohocken, Pennsylvania, USA The altogether exercise book article is to hand in return the duration of gain 59.Additional exact critical the minute button more than at one time may follow in multiple purchases CREDIT/DEBIT use strategy act openly INSTITUTIONAL PAYMENT ACCOUNT OR acquiring later Key: - casual delighted - remodelled delighted - Subscribed delighted - casual tentative delighted Website (c) 2007 Ingenta.
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